Festival of Genomics Boston - October 2017, Boston Convention Center

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2017 Agenda

Horizon Stages 1 & 2 
Our series of 20 minute keynotes from those doing the most essential work in the field. 

Prism Stage
Complex issues are channelled through the multiple perspectives and experiences of our panellists to help you illuminate the path forward.

In the Loop
This new forum leverages the undeniable wisdom of the Festival crowd to help you join the dots on critical issues. Places are limited for these, check back for more information.

Live Lounge
Pull up a beanbag and tune into bite sized insights from patients and clinicians, product demonstrations by leading solution providers, rare disease film screenings & a genomics play.

Book your pass today

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Themes

09.20
  1. Horizon Stage 1
    25 mins
    • Enabling Data
    • Data sharing
    • Data analysis
    • Data integration
    • Bioinformatics
    • Genomics data at scale • Exposing data to diverse scientists • Computational challenges and opportunities  
09.35
  1. Prism Stage
    50 mins
    • Precision Therapeutics
    • Research and Development
    • Data sharing
    • Data analysis
    • Data integration
    • Drug development
    • Clinical development
    • Collaborative models
    • CRISPR
    • Single cell
    • Pathology
    • Clinical implementation
    Learnings from the Genotype-Tissue Expression (GTEx) project How the Human Cell Atlas (HCA) will drive understanding of diagnosis, monitoring, and treatment of disease Existing and emerging technologi ...
09.50
  1. Horizon Stage 2
    25 mins
    • Precision Therapeutics
    • Data analysis
    • Drug development
    • Clinical development
    This talk will discuss several important factors in finding a suitable panel of biomarkers from a high dimensional assay.  Some of the main points will include: Impacts of filtering on finding a bioma ...
09.55
  1. In the Loop
    90 mins
    • Personalizing Medicine
    • Patient management
    • Clinical implementation
    Performance of key elements of the paradigm so far? What does success for PM look like? What are the real barriers in how to structure and deliver personalized care?  How do we make sure patients unde ...
10.50
  1. Horizon Stage 1
    25 mins
    • Precision Therapeutics
    • Drug development
11.00
  1. Live Lounge
    60 mins
    • Personalizing Medicine
    • Genetic testing
    • Genetic counselling
    • Patient management
    • Rare disease
    • Ethical/Legal/Social
    We welcome our friends at Disorder to host a session including a talk from Patricia Weltin, CEO and Founder of the Rare Disease United Foundation, showing of three inspiring short films (Imagine, Menk ...
  2. Prism Stage
    50 mins
    • Personalizing Medicine
    • Patient management
    • Clinical implementation
    • Insurance and payment
  3. Horizon Stage 2
    25 mins
    • Enabling Data
    • Data sharing
    • Data analysis
    • Data integration
    Role of cloud computing and machine learning in genomics. Impact and importance of All of Us Cohort Program. Potential for direct-to-patient approaches to transform clinical research
11.15
  1. Horizon Stage 1
    25 mins
    • Research and Development
    • Sequencing
    • Pathology
    Understanding the unique challenges in performing genomic assays from FFPE derived nucleic acids. The importance of isolating both DNA and RNA from a single FFPE sample.   New technologies and approac ...
11.25
  1. Horizon Stage 2
    25 mins
    • Enabling Data
    • Data analysis
    • Bioinformatics
    • How deskilling bioinformatics will reduce costs and produce results  • Nightmares on Genomics Row • Yes We Can! Experimental design to Interpretation without the complex command line of bioInformati ...
12.00
  1. Live Lounge
    15 mins
    • Enabling Data
    • Data analysis
    • AI/ Machine Learning
    Case study: how Data-Driven Medicine provides actionable insights for hereditary cancers
12.15
  1. Live Lounge
    15 mins
    • Research and Development
    • Sequencing
    Agencourt AMPure XP for purification and clean-up is optimized to meet the stringent needs of today’s genomic applications and to minimize the risk of losing important genetic information. • High reco ...
12.30
  1. Live Lounge
    15 mins
    Overview of Women In Bio’s mission and ongoing initiatives Discuss Greater Boston Chapter Introduce mentoring program, which will launch at the conference and aims to connect women with peers and advi ...
12.55
  1. In the Loop
    90 mins
    • Research and Development
    • Single cell
    • Sequencing
    • Comparing methodologies in exploring the genome, transcriptome and proteome of a single cell • How do we integrate data to generate a comprehensive view?   • How practical is an approach like this? 
13.05
  1. Horizon Stage 1
    25 mins
    • Research and Development
    • Drug development
    • CRISPR
    Intro to CRISPR-based viral diagnostics (sensitive, specific) Technical improvements to the method (cost, speed, ease of use) Application to a range of viruses
13.15
  1. Prism Stage
    50 mins
    • Precision Therapeutics
    • Drug development
    • Discover which strategies deliver the power to transform pipelines  • How can the broader community support the discovery and subsequent efficacy of new medicines? • Understand the vision for the fu ...
13.20
  1. Horizon Stage 2
    25 mins
    • Precision Therapeutics
    • Data analysis
    • AI/ Machine Learning
    • Data integration
    • Bioinformatics
    • Drug development
    • Clinical development
    • Collaborative models
    • Selecting the right drug combination for the right patient is very complex since drug resistance is heterogeneous and context specific. • AstraZeneca released >10,000 experimental results and partne ...
13.30
  1. Horizon Stage 1
    25 mins
    • Research and Development
    • CRISPR
    • CRISPR/Cas9 System: background & mechanism and Off-target reduction • Applications: gene knockout & insertion and transgenic animal models • New CRISPR Formats: epigenetic activators, synthetic gRNA ...
13.45
  1. Horizon Stage 2
    25 mins
    • Research and Development
    • Data sharing
    • Clinical development
    • Collaborative models
    The Type 2 Diabetes Knowledge Portal (T2DKP) democratizes access to large-scale genetic association and epigenetic data by aggregating them in an open-access framework The T2DKP provides both integrat ...
13.55
  1. Horizon Stage 1
    25 mins
    • Research and Development
    • CRISPR
    CRISPR/Cas9 off-target effects in vivo Compiled data from >80 mouse and rat projects Off-target predictability Reducing, avoiding, and monitoring off-targets
14.30
  1. Live Lounge
    25 mins
    • Sequencing
    •    What is Nanopore sensing •    How can Nanopore sensing be applied to sequencing long DNA molecules 10sk to 100sk bases of in real time •    Where scientists have performed Nanopore sequencing out ...
15.00
  1. Live Lounge
    15 mins
    • Research and Development
    • Collaborative models
    • CRISPR
    Learn about how BosLab provides a safe and inclusive BSL-1 laboratory space to anyone who wants to run their own biotechnology related project, workshop, event, class, or club!
15.05
  1. Horizon Stage 1
    25 mins
    • Personalizing Medicine
    • Genetic testing
    • Genetic counselling
    • Patient management
    • Clinical implementation
    • Ethical/Legal/Social
    The idea of precision medicine is often very different to the reality experienced by patients. Getting access to the specialists, expertise & tests you need to get a diagnosis is often incredibly diff ...
15.10
  1. Horizon Stage 2
    25 mins
    • Personalizing Medicine
    • Clinical development
    • Genetic testing
    • Patient management
    • Clinical implementation
15.20
  1. In the Loop
    90 mins
    • Precision Therapeutics
    • Drug development
    • Collaborative models
    Evaluating the merits of targeted collaboration with specific questions vs larger scale population studies e.g. UK biobank an All of US vs  precompetitive consortia  How can pre competitive collaborat ...
15.30
  1. Prism Stage
    50 mins
    • Precision Therapeutics
    • Data sharing
    • Data analysis
    • AI/ Machine Learning
    • Data integration
    • Bioinformatics
    • Drug development
    • Clinical development
    • Collaborative models
    • Patient management
    • Clinical implementation
    How will real world clinico-genomic datasets impact advancement of medical practice and drug development What challenges exist – data, technology, privacy – and how will we overcome them? Will the dat ...
  2. Horizon Stage 1
    25 mins
    • Personalizing Medicine
    • Genetic testing
    • Clinical implementation
    • Ethical/Legal/Social
    Genomic information is uniquely private The fate of medical privacy will be determined by how we protect genomic privacy CRISPR will have a powerful influence over how we define disease and disability
09.15
  1. Horizon Stage 1
    25 mins
    • Precision Therapeutics
    • Drug development
    • CRISPR
    • Sequencing
    - Perhaps the greatest surprise of human genome-wide association studies (GWAS) is that 90% of disease-associated regions do not affect proteins directly, but instead lie in non-coding regions with pu ...
09.25
  1. Horizon Stage 2
    25 mins
    • Precision Therapeutics
    • Clinical development
    • Genetic testing
    Update on FDA strategy to support precision medicine development  Insights into how FDA is promoting the generation of new genomic reference materials  How precisionFDA, an open-source cloud-based res ...
09.40
  1. Horizon Stage 1
    25 mins
    • Research and Development
    • AI/ Machine Learning
    • Sequencing
    Intro: SOPHIA GENETICS Understand the complexity of NGS The future of data-driven medicine
09.45
  1. Prism Stage
    50 mins
    • Personalizing Medicine
    • Data sharing
    • Collaborative models
    • Sequencing
    • Genetic testing
    • Patient management
    • Ethical/Legal/Social
    This panel will focus on “Game of Genomes,” a series of articles written for Stat by Carl Zimmer about his own genome Panelists will include scientists who analysed Zimmer’s genome to help him explore ...
09.50
  1. Horizon Stage 2
    25 mins
    • Research and Development
    • CRISPR
    • Ethical/Legal/Social
    Decision of The Patent Trial & Appeal Board in favor of the Broad Institute over University of California (UC) Prospects for Appeal by UC to U.S. Court of Appeals for the Federal Circuit Following tha ...
10.35
  1. Live Lounge
    10 mins
    • Personalizing Medicine
    • Genetic counselling
    • Patient management
    • Rare disease
  2. Horizon Stage 1
    25 mins
    • Personalizing Medicine
    • Genetic testing
    • Genetic counselling
    • Patient management
    • Clinical implementation
    • Insurance and payment
    How to launch a genomic medicine clinic  How whole genome sequencing is becoming a cost effective approach to diagnostic testing How diagnostic genome sequencing is integrated into routine genetic tes ...
10.45
  1. Live Lounge
    25 mins
    • Personalizing Medicine
    • Genetic testing
    • Genetic counselling
    • Patient management
    • Clinical implementation
  2. Horizon Stage 2
    25 mins
    • Precision Therapeutics
    • Drug development
    • Clinical development
    Review of cDx approvals in oncology Progression from single to multianalyte CDx tests New strategies to develop CDx for immune-oncology drugs Emerging collaborative models in pharma and academia to en ...
11.00
  1. Horizon Stage 1
    25 mins
    • Research and Development
    • Collaborative models
    • Sequencing
    On behalf of Advanced Analytical Technologies, Inc. 1. Technologies driving genomics are moving extremely rapidly 2. Get the right tools for the job
  2. Prism Stage
    50 mins
    • Research and Development
    • Drug development
    • CRISPR
    - Difficulties of off-target effects in CRISPR work - How can we accurately predict and monitor off-target effects?  - What advances/ areas to watch are there for reducing, avoiding and monitoring off ...
11.10
  1. Live Lounge
    30 mins
    • Personalizing Medicine
    • Genetic testing
    • Genetic counselling
    • Patient management
    • Clinical implementation
    What is the goal of genetic testing in rare diseases Why problematic situations for patients and families occur, with examples of unexpected consequences, ethical violations, and patient dilemmas How ...
  2. Horizon Stage 2
    25 mins
    • Research and Development
    • Drug development
    • Sequencing
    New capillary electrophoresis device for fragment analysis and Sanger sequencing Detection of genomic instability associated with DNA mismatch repair deficiency Utility of microsatellite instability ( ...
11.25
  1. Horizon Stage 1
    25 mins
    • Research and Development
    • Data sharing
    • Clinical development
    • Collaborative models
    • Genetic testing
    • Ethical/Legal/Social
12.00
  1. Live Lounge
    15 mins
    • Research and Development
    • Single cell
    • Sequencing
    Introduction to the technology behind BD Rhapsody Single-Cell Analysis System The advantages of the targeted sequencing approach to single cell genomics
12.15
  1. Live Lounge
    15 mins
    • Research and Development
    • Sequencing
    • Pathology
    •    Characterize immune escape and checkpoint mechanisms by gene expression •    Deconvolve immune-cell composition - quantitatively measure TILs   •    Estimate tumor foreignness through mutational ...
12.40
  1. Horizon Stage 1
    25 mins
    • Research and Development
    • Single cell
    Introduction to the technology behind BD Rhapsody, a high throughput single-cell analysis platform The advantages of the targeted sequencing approach to single cell genomics. The power of combining pr ...
12.55
  1. Live Lounge
    30 mins
    • Personalizing Medicine
    • Genetic testing
    • Genetic counselling
    • Patient management
    • Clinical implementation
    Who are genetic counselors How genetic counselors can assist families seeking a diagnosis How genetic counselors can educate and support families receiving a diagnosis
  2. In the Loop
    90 mins
    • Research and Development
    • Drug development
    • Collaborative models
    • Sequencing
    How to improve standards for tracking data  Creating a symphony from different lab instruments and providers How to effectively scale-up Quick, good or cheap. Lessons from a career of building and buy ...
13.00
  1. Horizon Stage 2
    25 mins
    • Enabling Data
    • Data sharing
    • Data integration
    • Drug development
    • Collaborative models
    The factors behind a major pharma’s effort to move genomics data processing and analysis to a public cloud environment in collaboration with a leading academic institution Unanticipated challenges ass ...
13.05
  1. Horizon Stage 1
    25 mins
    • Research and Development
    • Single cell
    Technology for high-throughput quantification of thousands of proteins in single mammalian cells Identifying cell states and cell fates from single cell proteomics data Exploring post-transcriptional ...
13.25
  1. Horizon Stage 2
    25 mins
    • Enabling Data
    • AI/ Machine Learning
    Brief introduction to deep learning Keys to success in deploying deep learning Applications of deep learning to life sciences problems
  2. Live Lounge
    30 mins
    • Personalizing Medicine
    • Clinical development
    • Collaborative models
    • Genetic testing
    • Genetic counselling
    • Patient management
    • Clinical implementation
    Pharma is seeking tools and methods to improve all aspects of drug development Includes the spectrum from Drug Discovery to late phase clinical trials in rare and common disease targets Greater awaren ...
13.30
  1. Horizon Stage 1
    25 mins
    • Research and Development
    • Single cell
    • Pathology
    Learn about the Digital Spatial Profiling (DSP) technology and workflow. Learn about how Digital Spatial Profiling (DSP) can deeply profile a variety of precious and heterogeneous tissue samples using ...
13.50
  1. Horizon Stage 2
    25 mins
    • Research and Development
    • Ethical/Legal/Social
    Learn about different types of funding and how to decide what’s right for you Learn how to talk to investors  Get answers to your questions
13.55
  1. Live Lounge
    25 mins
    • Personalizing Medicine
    • Genetic testing
    • Genetic counselling
    • Patient management
    • Clinical implementation
    Enable the learner to describe a personal experience of living with stroke and Moyamoya disease  Enable the learner to discuss volunteerism and advocacy options for patients Enable the learner to iden ...
  2. Horizon Stage 1
    25 mins
    • Research and Development
    • Single cell
    Batching processing and data integration Comprehensive QC and report User friendly data sharing
15.05
  1. Prism Stage
    50 mins
    • Personalizing Medicine
    • Precision Therapeutics
    • Drug development
    • Clinical development
    • Sequencing
    • Pathology
    • Patient management
    • Clinical implementation
    How do we assign anatomic origin to liquid biopsy samples? How do we manage signal vs. noise? Which type of liquid biopsy (CTCs, exosomes, nucleic acids, etc.) will be useful in a given setting?
  2. Live Lounge
    45 mins
    • Personalizing Medicine
    • Genetic testing
    • Genetic counselling
    • Patient management
    • Clinical implementation
  3. In the Loop
    90 mins
    • Enabling Data
    • Precision Therapeutics
    • Data sharing
    • Data analysis
    • Data integration
    • Bioinformatics
    • Drug development
    What is missing to improve use of genomic data for precision medicine, what takes too long, what is too complex? Where are the advantages/disadvantages of cloud-based infrastructures for exchanging an ...
  4. Horizon Stage 1
    25 mins
    • Enabling Data
    • Data sharing
    • Data analysis
    • Data integration
    • Drug development
    Use of Berg Bayesian AI brings together diverse biological data sets into a causal map AI-driven biology is able to elucidate “new biology” leading to new class of biologically-based targets AI can be ...
15.10
  1. Horizon Stage 2
    25 mins
    • Enabling Data
    • Data sharing
    • Data analysis
    • AI/ Machine Learning
    • Data integration
    • Bioinformatics
    ● Intro to machine learning/deep learning ● Recasting variant calling as image classification problem enables efficient transfer learning ● Model generalizes across technical variation, sequence cover ...

Exhibitors


 

Sponsors & Exhibitors

Founding Partners

Illumina, Roche and Thermo Fisher Scientific

Strategic Partners

Agilent Technologies, Beckman Coulter Life Sciences, SevenBridges and Twist Bioscience

Supporters

With thanks to our supporters

 

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